Publications
| 2023 | Griewahn L, Müller-Foxworth M, Peintner L, Wissler M, Weiss M, Brauns-Schubert P, Massoumi R, Borner C, Groß O, Yabal M, Charvet C, Maurer U. SPATA2 restricts OTULIN-dependent LUBAC activity independently of CYLD. Cell Rep. 2023 Jan 31;42(1):111961. doi: 10.1016/j.celrep.2022.111961. Epub 2023 Jan 12. PMID: 36640323. |
| 2021 | Bernardi C, Maurer G, Ye T, Marchal P, Jost B, Wissler M, Maurer U, Kastner P, Chan S, Charvet C. CD4+ T cells require Ikaros to inhibit their differentiation toward a pathogenic cell fate. Proc Natl Acad Sci U S A. 2021 Apr 27;118(17):e2023172118. doi: 10.1073/pnas.2023172118. PMID: 33893236; PMCID: PMC8092604. |
| 2019 | Griewahn L, Köser A, Maurer U. Keeping Cell Death in Check: Ubiquitylation-Dependent Control of TNFR1 and TLR Signaling. Front Cell Dev Biol. 2019 Jun 28;7:117. doi: 10.3389/fcell.2019.00117. eCollection 2019. Pubmed31316982 |
| 2018 | Faletti L, Peintner L, Neumann S, Sandler S, Grabinger T, Mac Nelly S, Merfort I, Huang CH, Tschaharganeh D, Kang TW, Heinzmann F, D'Artista L, Maurer U, Brunner T, Lowe S, Zender L, Borner C. TNFα sensitizes hepatocytes to FasL-induced apoptosis by NFκB-mediated Fas upregulation. Cell Death Dis. 2018 Sep 5;9(9):909. doi: 10.1038/s41419-018-0935-9. Pubmed30185788 |
| Haun F, Neumann S, Peintner L, Wieland K, Habicht J, Schwan C, Østevold K, Koczorowska MM, Biniossek M, Kist M, Busch H, Boerries M, Davis RJ, Maurer U, Schilling O, Aktories K, Borner C. Identification of a novel anoikis signalling pathway using the fungal virulence factor gliotoxin. Nat Commun. 2018 Aug 30;9(1):3524. doi: 10.1038/s41467-018-05850-w. Pubmed30166526 | |
| Schubert F, Rapp J, Brauns-Schubert P, Schlicher L, Stock K, Wissler M, Weiß M, Charvet C, Borner C, Maurer U. Requirement of GSK-3 for PUMA induction upon loss of pro-survival PI3K signaling. Cell Death Dis. 2018 Apr 23;9(5):470. doi: 10.1038/s41419-018-0502-4. Pubmed29686375 | |
| Brauns-Schubert P, Schubert F, Wissler M, Weiss M, Schlicher L, Bessler S, Safavi M, Miething C, Borner C, Brummer T, Maurer U. CDK9-mediated phosphorylation controls the interaction of TIP60 with the transcriptional machinery. EMBO Rep. 2018 Feb;19(2):244-256. doi: 10.15252/embr.201744311. Epub 2018 Jan 15. Pubmed29335245 | |
| 2017 | Schlicher L, Brauns-Schubert P, Schubert F, Maurer U. SPATA2: more than a missing link. Cell Death Differ. 2017 Jul;24(7):1142-1147. doi: 10.1038/cdd.2017.26. Epub 2017 Mar 10. Pubmed28282038 |
| Schlicher L, Maurer U. SPATA2: new insights in the assembly of the TNFR signaling complex. Cell Cycle.2017 Jan 2;16(1):11-12. doi: 10.1080/15384101.2016.1232090. Epub 2016 Sep 16. Pubmed27635695 | |
| 2016 | Schlicher L, Wissler M, Preiss F, Brauns-Schubert P, Jakob C, Dumit V, Borner C, Dengjel J, Maurer U. SPATA2 promotes CYLD activity and regulates TNF-induced NF-κB signaling and cell death. EMBO Rep. 2016 Oct;17(10):1485-1497. Epub 2016 Jul 25. Pubmed27458237 |
| Peintner L, Novelli F, Smirnov A, Maurer U, Borner C, von Karstedt S. 9th Tuscany Retreat on Cancer Research: genetic profiling, resistance mechanisms and novel treatment concepts in cancer. Cell Death Differ. 2016 Jan;23(1):183-4. doi: 10.1038/cdd.2015.148. Epub 2015 Nov 13. Pubmed26564399 | |
| 2015 | Neumann S, Maadidi SE, Faletti L, Haun F, Labib S, Schejtman A, Maurer U, Borner C. How do viruses control mitochondria-mediated apoptosis? Virus Res. 2015 Nov 2;209:45-55. doi: 10.1016/j.virusres.2015.02.026. Epub 2015 Mar 1Pubmed25736565 |
| Papaianni E, El Maadidi S, Schejtman A, Neumann S, Maurer U, Marino-Merlo F, Mastino A, Borner C. Phylogenetically Distant Viruses Use the Same BH3-Only Protein Puma to Trigger Bax/Bak-Dependent Apoptosis of Infected Mouse and Human Cells. PLoS One. 2015 Jun 1;10(6):e0126645. doi: 10.1371/journal.pone.0126645. eCollection 2015. Pubmed26030884 | |
| 2014 | Lindner SE, Wissler M, Gründer A, Aumann K, Ottina E, Peintner L, Brauns-Schubert P, Preiss F, Herzog S, Borner C, Charvet C, Villunger A, Pahl HL, Maurer U. Increased leukocyte survival and accelerated onset of lymphoma in the absence of MCL-1 S159-phosphorylation. Oncogene. 2014 Oct 30;33(44):5221-4. doi: 10.1038/onc.2013.469. Epub 2013 Nov 11. Pubmed24213575 |
| Maurer U, Preiss F, Brauns-Schubert P, Schlicher L, Charvet C. GSK-3 - at the crossroads of cell death and survival. J Cell Sci. 2014 Apr 1;127(Pt 7):1369-78. doi: 10.1242/jcs.138057. Pubmed24687186 | |
| El Maadidi S, Faletti L, Berg B, Wenzl C, Wieland K, Chen ZJ, Maurer U, Borner C. A novel mitochondrial MAVS/Caspase-8 platform links RNA virus-induced innate antiviral signaling to Bax/Bak-independent apoptosis. J Immunol. 2014 Feb 1;192(3):1171-83. doi: 10.4049/jimmunol.1300842. Epub 2014 Jan 3. Pubmed24391214 | |
| 2013 | Geissler A, Haun F, Frank DO, Wieland K, Simon MM, Idzko M, Davis RJ, Maurer U, Borner C. Apoptosis induced by the fungal pathogen gliotoxin requires a triple phosphorylation of Bim by JNK. Cell Death Differ. 2013 Oct;20(10):1317-29. doi: 10.1038/cdd.2013.78. Epub 2013 Jul 5. Pubmed23832115 |
| 2012 | Vogel S, Raulf N, Bregenhorn S, Biniossek ML, Maurer U, Czabotar P, Borner C. Cytosolic Bax: Does it require binding proteins to keep its pro-apoptotic activity in check? J Biol Chem. 2012 Mar 16;287(12):9112-27. Epub 2012 Jan 25. Pubmed22277657 |
| 2011 | Charvet C, Maurer U. Cell Cycle. GSK-3 turns p53 deadly. 2011 Nov 1;10(21):3621-2. Pubmed22033176 |
| Charvet C, Wissler M, Brauns-Schubert P, Wang SJ, Tang Y, Sigloch FC, Mellert H, Brandenburg M, Lindner SE, Breit B, Green DR, McMahon SB, Borner C, Gu W, Maurer U. Phosphorylation of Tip60 by GSK-3 Determines the Induction of PUMA and Apoptosis by p53. Mol Cell. 2011 Jun 10;42(5):584-96. Pubmed21658600 | |
| 2009 | Baudot AD, Jeandel PY, Mouska X, Maurer U, Tartare-Deckert S, Raynaud SD, Cassuto JP, Ticchioni M, Deckert M. The tyrosine kinase Syk regulates the survival of chronic lymphocytic leukemia B cells through PKCdelta and proteasome-dependent regulation of Mcl-1 expression. Oncogene. 2009 Sep 17;28(37):3261-73. Epub 2009 Jul 6. Pubmed19581935 |
| 2008 | Walter D, Schmich K, Vogel S, Pick R, Kaufmann T, Hochmuth FC, Haber A, Neubert K, McNelly S, von Weizsäcker F, Merfort I, Maurer U, Strasser A, Borner C. Switch from type II to I Fas/CD95 death signaling on in vitro culturing of primary hepatocytes. Hepatology. 2008 Dec;48(6):1942-53. Pubmed19003879 |
| 2007 | Colell A, Ricci JE, Tait S, Milasta S, Maurer U, Bouchier-Hayes L, Fitzgerald P, Guio-Carrion A, Waterhouse NJ, Li CW, Mari B, Barbry P, Newmeyer DD, Beere HM, Green DR. GAPDH and autophagy preserve survival after apoptotic cytochrome c release in the absence of caspase activation. Cell. 2007 Jun 1;129(5):983-97, Pubmed17540177 |
| 2006 | Charvet C, Canonigo AJ, Becart S, Maurer U, Miletic AV, Swat W, Deckert M, Altman A: Vav1 promotes T cell cycle progression by linking TCR/CD28 costimulation to FOXO1 and p27kip1 expression. J Immunol. 2006 Oct 15;177(8):5024-31, Pubmed17015685 |
| Maurer U, Spierings DCJ, McStay G, Bender C, Saleh M, Chipuk J, Green DR:Mitochondrial Pathway of Apoptosis: Antiapoptotic Bcl-2 Family Sci. STKE 2006 (Connections Map Pathway), Science | |
| Manoharan A, Kiefer T, Leist S, Schrader K, Urban C, Walter D, Maurer U, Borner C. Identification of a 'genuine' mammalian homolog of nematodal CED-4: is the hunt over or do we need better guns? Cell Death Differ 13, 877 – 1047, Pubmed16691212 | |
| Maurer U, Charvet C, Wagman AS, Dejardin E, Green DR. Glycogen synthase kinase-3 regulates mitochondrial outer membrane permeabilization and apoptosis by destabilization of MCL-1. Mol Cell. 2006 Mar 17;21(6):749-60. Pubmed16543145 | |
| 2005 | Spierings D, McStay G, Saleh M, Bender C, Chipuk J, Maurer U, Green DR. Connected to death: the (unexpurgated) mitochondrial pathway of apoptosis. Science. 2005 Oct 7;310(5745):66-7. Pubmed16210526 |
| 2004 | Viatour P, Dejardin E, Warnier M, Lair F, Claudio E, Bureau F, Marine JC, Merville MP, Maurer U, Green D, Piette J, Siebenlist U, Bours V, Chariot A. GSK3-mediated BCL-3 phosphorylation modulates its degradation and its oncogenicity. Mol Cell. 2004 Oct 8;16(1):35-45. Pubmed15469820 |
| 2003 | Chipuk JE, Maurer U, Green DR, Schuler M. Pharmacologic activation of p53 elicits Bax-dependent apoptosis in the absence of transcription. Cancer Cell. 2003 Nov;4(5):371-81. Pubmed14667504 |
| Schuler M, Maurer U, Goldstein JC, Breitenbucher F, Hoffarth S, Waterhouse NJ, Green DR. p53 triggers apoptosis in oncogene-expressing fibroblasts by the induction of Noxa and mitochondrial Bax translocation. Cell Death Differ. 2003 Apr;10(4):451-60. Pubmed12719722 | |
| Hubinger G, Wehnes E, Xue L, Morris SW, Maurer U. Hammerhead ribozyme-mediated cleavage of the fusion transcript NPM-ALK associated with anaplastic large-cell lymphoma. Exp Hematol. 2003 Mar;31(3):226-33. Pubmed12644020 | |
| 2002 | Hubinger G, Schmid M, Linortner S, Manegold A, Bergmann L, Maurer U. Ribozyme-mediated cleavage of wt1 transcripts suppresses growth of leukemia cells. Exp Hematol. 2001 Oct;29(10):1226-35. Pubmed11602325 |
| Bonzon C, Droin NM, Maurer U, Ricci JE. Death in paradise.Cell Death Differ. 2002 Jul;9(7):780-2. No abstract available. Pubmed12058283 | |
| Karakas T, Miething CC, Maurer U, Weidmann E, Ackermann H, Hoelzer D, Bergmann L. The coexpression of the apoptosis-related genes bcl-2 and wt1 in predicting survival in adult acute myeloid leukemia. Leukemia. 2002 May;16(5):846-54. Pubmed11986946 | |
| 2001 | Graf J, Merk B, Maurer U, Muller E, Bergmann L. Identification of novel polymorphisms in intron 7 of the human p53 gene in acute myeloid leukemia and healthy donors. Leuk Lymphoma. 2001 May;41(5-6):655-8. Pubmed11378583 |
| Maurer U, Jehan F, Englert C, Hubinger G, Weidmann E, DeLuca HF, Bergmann L. The Wilms' tumor gene product (WT1) modulates the response to 1,25-dihydroxyvitamin D3 by induction of the vitamin D receptor.J Biol Chem. 2001 Feb 9;276(6):3727-32. Epub 2000 Oct 24. Pubmed11050081 | |
| 2000 | Greiner J, Ringhoffer M, Simikopinko O, Szmaragowska A, Huebsch S, Maurer U, Bergmann L, Schmitt M. Simultaneous expression of different immunogenic antigens in acute myeloid leukemia. Exp Hematol. 2000 Dec;28(12):1413-22. Pubmed11146163 |
| 1998 | Karakas T, Maurer U, Weidmann E, Miething CC, Hoelzer D, Bergmann L.High expression of bcl-2 mRNA as a determinant of poor prognosis in acute myeloid leukemia. Ann Oncol. 1998 Feb;9(2):159-65. Pubmed9553660 |
| 1997 | Maurer U, Weidmann E, Karakas T, Hoelzer D, Bergmann L. Wilms tumor gene (wt1) mRNA is equally expressed in blast cells from acute myeloid leukemia and normal CD34+ progenitors. Blood. 1997 Nov 15;90(10):4230-2. Pubmed9354696 |
| Maurer U, Brieger J, Weidmann E, Mitrou PS, Hoelzer D, Bergmann L. The Wilms' tumor gene is expressed in a subset of CD34+ progenitors and downregulated early in the course of differentiation in vitro. Exp Hematol. 1997 Aug;25(9):945-50. Pubmed9257807 | |
| Bergmann L, Miething C, Maurer U, Brieger J, Karakas T, Weidmann E, Hoelzer D. High levels of Wilms' tumor gene (wt1) mRNA in acute myeloid leukemias are associated with a worse long-term outcome.Blood. 1997 Aug 1;90(3):1217-25. Pubmed9242555 | |
| Bergmann L, Maurer U, Weidmann E. Wilms tumor gene expression in acute myeloid leukemias.Leuk Lymphoma. 1997 May;25(5-6):435-43. Review. Pubmed9250813 | |
| Weidmann E, Brieger J, Karakas T, Maurer U, Pascheberg U, Hoelzer D, Mitrou PS, Bergmann L. Establishment and characterization of a new, factor-independent acute myeloid leukemia line designated Ei501. Leukemia. 1997 May;11(5):709-13. Pubmed9180296 | |
| 1995 | Brieger J, Weidmann E, Maurer U, Hoelzer D, Mitrou PS, Bergmann L.The Wilms' tumor gene is frequently expressed in acute myeloblastic leukemias and may provide a marker for residual blast cells detectable by PCR. Ann Oncol. 1995 Oct;6(8):811-6. Pubmed8589020 |